Describing the neuroscientific basis for effective psychotherapy, Professor Holmes draws on the Free Energy Principle, which holds that, through 'active inference' - agency and model revision - the brain minimises discrepancies between incoming experience and its pre-existing picture of the world.

Describing the neuroscientific basis for effective psychotherapy, Professor Holmes draws on the Free Energy Principle, which holds that, through 'active inference' - agency and model revision - the brain minimises discrepancies between incoming experience and its pre-existing picture of the world.